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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment selection for chronic weight loss in addition to a reduced-calorie diet and physical activity.

Using two separate drugs to shed pounds can be very effective you will find combinations before the FDA now awaiting approval. When dealing with weight loss and the individuals who go through it you need to err to the side of caution and allow the FDA do its job and demand some study be done so the public is aware of the side effects and dangers of the medications before we drive them. Keep in mind that drug companies will be in business to earn money and that they would say everything to keep people on his or her medications.

Researchers found out that participants using this drug for any year, lost excess weight within four weeks and have kept the load off throughout the 56 weeks from the study. Contrave is often a combination of the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which are made up of multiple active ingredient, which can make them more effective and safer.

Combo-pilling could be the newest fad or in addition to this the newest in the future under scrutiny and for that reason it is just more publicly known recently, comb-pilling for weight loss has been around since the eighties. The biggest reason that utilizing a combination of pills is starting to become popular will be the fact that as of right now there aren't any long term prescription slimming capsules that have been approved by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications and some of the combinations have been rejected or have yet to be approved by the FDA.

Seizures can be a side effect with Contrave and must not be taken in people with seizure disorders. The drug can also raise blood pressure level and heartrate, and must not be used in individuals with a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise blood pressure level and heartrate and must 't be used in patients with uncontrolled high hypertension, along with by you are not heart-related and cerebrovascular (circulation dysfunction impacting the brain) disease. Patients which has a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes having a boxed warning to alert medical researchers and patients on the increased chance of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for smoking cessation.

Most of the combinations that are used to enhance weight reduction involve an amphetamine and an antidepressant. Phentermine and Prozac certainly are a popular combination which have been around for a while, and although it has been around stuffed to truly combine the 2 and try to get FDA approval to market it as a weight reduction pill. Right there should raise some red flags if the greedy pharmaceutical companies don't want to be involved in combining medications and selling them something must be wrong using the combination. In fairness there exists one weight reduction combination pill that is certainly in front of the FDA now Contrave?which couples naltrexone, employed to treat alcohol and abusing drugs, with all the antidepressant bupropion (Wellbutrin, Zyban) it is often given the just do it to move forward by an FDA advisory committee, but since yet hasn't been approved.